Takahashi S, Kyogoku H, Hayakawa T, Miura H, Oji A, Kondo Y, Takebayashi S, Kitajima TS, and Hiratani I. Embryonic genome instability upon DNA replication timing program emergence. Nature (in press)

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Hayakawa T, Yamamoto A, Yoneda T, Hori S, Okochi N, Kagotani K, Okumura K, and Takebayashi S. Reorganization of the DNA replication landscape during adipogenesis is closely linked with adipogenic gene expression. J. Cell Sci.136: jcs260778, 2023.

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Sakamoto M, Hori S, Yoneda T, Yamamoto A, Kuriya K, and Takebayashi S. scRepli-Seq: A Powerful Tool to Study Replication Timing and Genome Instability. Cytogenet. Genome Res. 162:161-170, 2022.    

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Hayakawa T, Suzuki R, Kagotani K, Okumura K, and Takebayashi S I*. Camptothecin-induced replication stress affects DNA replication profiling by E/L Repli-seq. Cytogenetic and Genome Research 161:437-444, 2021.

 

Takebayashi S. I*, Ryba T, Wimbish K, Hayakawa T, Sakaue M, Kuriya K, Takahashi S, Ogata S, Hiratani I, Okumura K, Okano M, and Ogata M. The temporal order of DNA replication shaped by mammalian DNA methyltransferases. Cells 10:266, 2021.

 

Miura H, Takahashi S, Shibata T, Nagao K, Obuse C, Okumura K, Ogata M, Hiratani I, and Takebayashi S I*. Mapping replication timing domains genome wide in single mammalian cells with single-cell DNA replication sequencing. Nat. Protoc. 15:4058-4100, 2020.

 

Tanaka H, Igata T, Etoh K, Koga T, Takebayashi S I, and Nakao M. The NSD2/WHSC1/MMSET methyltransferase prevents cellular senescence-associated epigenomic remodeling. Aging Cell 19:e13173, 2020.

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Ikuno A, Akeda K, Takebayashi S I, Shimaoka M, Okumura K, and Sudo A. Genome-wide Analysis of DNA Methylaton Identifies Differentially Methylated Loci Associated With Human Intervertebral Disc Degeneration. PLoS One 14: e0222188, 2019.

 

Miura H, Takahashi S, Poonperm R, Tanigawa A, Takebayashi S I, and Hiratani I. Single-cell DNA Replication Profiling Identifies Spatiotemporal Developmental Dynamics of Chromosome Organization. Nat. Genet. 51: 1356-1368, 2019.

 

Takahashi S, Miura H, Shibata T, Nagao K, Okumura K, Ogata M, Obuse C, Takebayashi S I*, and Hiratani I. Genome-wide Stability of the DNA Replication Program in Single Mammalian Cells. Nat. Genet. 51: 529-540, 2019.

 

Okamura M, Yamanaka Y, Shigemoto M, Kitadani Y, Kobayashi Y, Kambe T, Nagao M, Kobayashi I, Okumura K, and Masuda S. Depletion of mRNA export regulator DBP5/DDX19, GLE1 or IPPK that is a key enzyme for the production of IP6, resulting in differentially altered cytoplasmic mRNA expression and specific cell defect. PLoS One 13: e0197165, 2018.

 

Takebayashi S I*, Ogata S, Ogata M, and Okumura K. Mapping mammalian replication domains using the ion torrent semiconductor sequencing platform. Biosci. Biotechnol. Biochem. 82: 2098-2100, 2018.

 

平谷伊智朗、竹林慎一郎「複製タイミングと間期染色体構築」実験医学、pp2933-2940, 2018.

 

Tanaka H, Takebayashi S I, Sakamoto A, Igata T, Nakatsu Y, Saitoh N, Hino S, and Nakao M. The SETD8/PR-Set7 Methyltransferase Functions as a Barrier to Prevent Senescence-Associated Metabolic Remodeling. Cell Rep. 18: 2148-2161, 2017.

 

Wakida T, Ikura M, Kuriya K, Ito S, Shiroiwa Y, Habu T, Kawamoto T, Okumura K, Ikura T, and Furuya K. The CDK-PLK1 axis targets the DNA damage checkpoint sensor protein RAD9 to promote cell proliferation and tolerance to genotoxic stress.

Elife 6: e29953, 2017.

 

Takebayashi S*, Ogata M, and Okumura K*. Anatomy of Mammalian Replication Domains. Genes (Basel) 8: E110, 2017.

 

Izumi M, Mizuno T, Yanagi KI, Sugimura K, Okumura K, Imamoto N, Abe T, and Hanaoka F. The Mcm2-7-interacting domain of human mini-chromosome maintenance 10 (Mcm10) protein is important for stable chromatin association and origin firing. J. Biol. Chem. 292: 13008-13021, 2017.

 

Hassan W, Takebayashi S, Abdalla M O, Fujino K, Kudoh S, Motooka Y, Sato Y, Naito Y, Higaki K, Wakimoto J, Okada S, Nakao M, Ishikawa Y, and Ito T. Correlation between Histone Acetylation and Expression of Notch1 in Human Lung Carcinoma and Its Possible Role in Combined Small Cell Lung Carcinoma. Lab. Invest. 97: 913-921, 2017.

 

Kuriya K, Higashiyama E, Avşar-Ban E, Okochi N, Hattori K, Ogata S, Takebayashi S I, Ogata M, Tamaru Y, and Okumura K*. Direct visualization of replication dynamics in early zebrafish embryos. Biosci. Biotechnol. Biochem. 29: 1-4, 2016.

 

Ito S, Ohmi A, Sakamiya A, Yano T, Okumura K, Nishimura N, and Kagontani K. Ginger hexane extract suppresses RANKL-induced osteoclast differentiation.

Biosci. Biotechnol. Biochem. 80: 779-785, 2016.

 

Kuriya K, Higashiyama E, Avşar-Ban E, Tamaru Y, Ogata S, Takebayashi S, Ogata M, and Okumura K*. Direct Visualization of DNA Replication Dynamics in Zebrafish Cells. Zebrafish 12: 432-439, 2015.

 

Takebayashi S, Tanaka H, Hino S, Nakatsu Y, Igata T, Sakamoto A, Narita M, and Nakao M. Retinoblastoma protein promotes oxidative phosphorylation through upregulation of glycolytic genes in oncogene-induced senescent cells. Aging Cell 14: 689-697, 2015.

 

Matsuda T, Matsushima M, Nabemoto M, Osaka M, Sakazono S, Masuko-Suzuki H, Takahashi H, Nakazono M, Iwano M, Takayama S, Shimizu KK, Okumura K, Suzuki G, Watanabe M, Suwabe K. Transcriptional characteristics and differences in Arabidopsis stigmatic papilla cells pre- and post-pollination. Plant Cell Physiol. 56: 663-673, 2015

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